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Northwestern University Feinberg School of Medicine
Department of Pediatrics

Critical Care Publications

Below are recent publications by faculty members in the Division of Critical Care in the Department of Pediatrics at Northwestern University Feinberg School of Medicine.

Recent PubMed Publications

  1. Badke CM, Carroll MS, Pendergrast TR, Weese-Mayer DE, Sanchez-Pinto LN  Assessing bedside measures of autonomic nervous system dysregulation in the PICU.  Pediatr Res  2025 Feb 06;. doi:10.1038/s41390-024-03778-0
  2. Campos MA, Riha IA, Zhang C, Mozes C, Scheidt KA, Zhang X  Discovery of DCAF16 Binders for Targeted Protein Degradation.  ACS Chem Biol  2025 Jan 30;. doi:10.1021/acschembio.4c00799
  3. Badke CM, Wang A, Daniels LA, Sanchez-Pinto LN  Validation of Pediatric Sequential Organ Failure Assessment (pSOFA) Scores to Predict Critical Events in the Pediatric Intensive Care Unit.  J Intensive Care Med  2025 Jan 09;:8850666241307630. doi:10.1177/08850666241307630
  4. Michelson KN, Fishman AC, Feinberg EC, Ross S, Wald HS, Auerbach C, Roth S  Antisemitism in American Healthcare: A Survey Study of Reported Experiences.  J Gen Intern Med  2024 Dec 11;. doi:10.1007/s11606-024-09159-x
  5. Riha IA, Campos MA, Jin X, Wang FY, Zhang C, Dunne SF, Cravatt BF, Zhang X  Exploiting the DCAF16-SPIN4 interaction to identify DCAF16 ligands for PROTAC development.  RSC Med Chem  2024 Dec 06;. doi:10.1039/d4md00681j
  6. Zhang C, Zhou C, Magassa A, Jin X, Fang D, Zhang X  A platform for mapping reactive cysteines within the immunopeptidome.  Nat Commun  2024 Nov 08;15(1):9698. pii:9698
  7. Asp RA, Paquette ET  Parent Perspectives on Social Risk Screening in the PICU.  Pediatr Crit Care Med  2024 Oct 01;25(10):953-958. doi:10.1097/PCC.0000000000003580
  8. Heneghan JA, Akande MY, Ramgopal S, Evans MD, Hallman M, Goodman DM  New Morbidities During Critical Illness and Associated Risk of ICU Readmission: Virtual Pediatric Systems Cohort, 2017-2020.  Pediatr Crit Care Med  2024 Oct 01;25(10):e405-e409. doi:10.1097/PCC.0000000000003542
  9. Zhang X, Duan S, Apostolou PE, Wu X, Watanabe J, Gallitto M, Barron T, Taylor KR, Woo PJ, Hua X  et al.  CHD2 Regulates Neuron-Glioma Interactions in Pediatric Glioma.  Cancer Discov  2024 Sep 04;14(9):1732-1754. doi:10.1158/2159-8290.CD-23-0012
  10. Setar L, Lee JG, Sanchez-Pinto LN, Coates BM  Accuracy and Interpretation of Transcutaneous Carbon Dioxide Monitoring in Critically Ill Children.  Pediatr Crit Care Med  2024 Sep 01;25(9):e372-e379. doi:10.1097/PCC.0000000000003564
  11. Sanchez-Pinto LN, Del Pilar Arias López M, Scott H, Gibbons K, Moor M, Watson RS, Wiens MO, Schlapbach LJ, Bennett TD  Digital solutions in paediatric sepsis: current state, challenges, and opportunities to improve care around the world.  Lancet Digit Health  2024 Sep;6(9):e651-e661. doi:10.1016/S2589-7500(24)00141-9
  12. Ashworth RC, Malone JR, Franklin D, Sorce LR, Clayman ML, Frader J, White DB, Michelson KN  Associations of Patient and Parent Characteristics With Parental Decision Regret in the PICU: A Secondary Analysis of the 2015-2017 Navigate Randomized Comparative Trial.  Pediatr Crit Care Med  2024 Sep 01;25(9):795-803. doi:10.1097/PCC.0000000000003534
  13. Liu B, Yi D, Xia X, Ramirez K, Zhao H, Cao Y, Tripathi A, Dong R, Gao A, Ding H  et al.  General Capillary Endothelial Cells Undergo Reprogramming Into Arterial Endothelial Cells in Pulmonary Hypertension Through HIF-2α/Notch4 Pathway.  Circulation  2024 Jul 30;150(5):414-417. doi:10.1161/CIRCULATIONAHA.123.067981
  14. Zhang X, Blackwell CK, Moore J, Liu SH, Liu C, Forrest CB, Ganiban J, Stroustrup A, Aschner JL, Trasande L  et al.  Associations between neighborhood characteristics and child well-being before and during the COVID-19 pandemic: A repeated cross-sectional study in the Environmental influences on Child Health Outcomes (ECHO) program.  Environ Res  2024 Jul 01;252(Pt 1):118765. doi:10.1016/j.envres.2024.118765
  15. Bennett TD, Argent AC, Sanchez-Pinto LN  Phoenix Criteria for Pediatric Sepsis and Septic Shock-Reply.  JAMA  2024 Jun 18;331(23):2050-2051. doi:10.1001/jama.2024.8202
  16. Atreya MR, Bennett TD, Geva A, Faustino EVS, Rogerson CM, Lutfi R, Cvijanovich NZ, Bigham MT, Nowak J, Schwarz AJ  et al.  Biomarker Assessment of a High-Risk, Data-Driven Pediatric Sepsis Phenotype Characterized by Persistent Hypoxemia, Encephalopathy, and Shock.  Pediatr Crit Care Med  2024 Jun 01;25(6):512-517. doi:10.1097/PCC.0000000000003499
  17. Zurawel AA, Coates BM  Time to split: biomarker trajectories in pediatric acute respiratory distress syndrome hint at underlying disease.  J Clin Invest  2024 May 15;134(10). pii:e180662
  18. Liu B, Yi D, Li S, Ramirez K, Xia X, Cao Y, Zhao H, Tripathi A, Qiu S, Kala M  et al.  Single-cell and Spatial Transcriptomics Identified Fatty Acid-binding Proteins Controlling Endothelial Glycolytic and Arterial Programming in Pulmonary Hypertension.  bioRxiv  2024 Apr 15;. pii:2024.02.11.579846
  19. Sanchez-Pinto LN, Bennett TD, DeWitt PE, Russell S, Rebull MN, Martin B, Akech S, Albers DJ, Alpern ER, Balamuth F  et al.  Development and Validation of the Phoenix Criteria for Pediatric Sepsis and Septic Shock.  JAMA  2024 Feb 27;331(8):675-686. doi:10.1001/jama.2024.0196
  20. Rissman L, Paquette ET  Family Challenges and Navigator Support: It is Time We Support Our Families Better.  Pediatr Crit Care Med  2024 Feb 01;25(2):180-182. doi:10.1097/PCC.0000000000003403
  21. Tager JB, Hinojosa JT, LiaBraaten BM, Balistreri KA, Aniciete D, Charleston E, Frader JE, White DB, Clayman ML, Sorce LR  et al.  Challenges of Families of Patients Hospitalized in the PICU: A Preplanned Secondary Analysis From the Navigate Dataset.  Pediatr Crit Care Med  2024 Feb 01;25(2):128-138. doi:10.1097/PCC.0000000000003385
  22. Walker SB, Winters JM, Schauer JM, Murphy P, Fawcett A, Sanchez-Pinto LN  Performance of Tools and Measures to Predict Fluid Responsiveness in Pediatric Shock and Critical Illness: A Systematic Review and Meta-Analysis.  Pediatr Crit Care Med  2024 Jan 01;25(1):24-36. doi:10.1097/PCC.0000000000003320
  23. Prigge AD, Coates BM  Can Airway Monocytes from Premature Infants Teach Us about Macrophage Differentiation in the Lungs?  Am J Respir Cell Mol Biol  2023 Dec;69(6):612-613. doi:10.1165/rcmb.2023-0305ED
  24. Rogerson CM, Abu-Sultaneh S, Loberger JM, Ross P, Khemani RG, Sanchez-Pinto LN  Predicting Duration of Invasive Mechanical Ventilation in the Pediatric ICU.  Respir Care  2023 Nov 25;68(12):1623-1630. doi:10.4187/respcare.11015
  25. Dai Z, Thorp EB  New Way to Study Pulmonary Hypertension in HFpEF.  Circ Res  2023 Nov 10;133(11):899-901. doi:10.1161/CIRCRESAHA.123.323753
  26. Wösten-van Asperen RM, la Roi-Teeuw HM, van Amstel RB, Bos LD, Tissing WJ, Jordan I, Dohna-Schwake C, Bottari G, Pappachan J, Crazzolara R  et al.  Distinct clinical phenotypes in paediatric cancer patients with sepsis are associated with different outcomes-an international multicentre retrospective study.  EClinicalMedicine  2023 Nov;65:102252. pii:102252
  27. Zhao Y, Li C, Zhang S, Cheng J, Liu Y, Han X, Wang Y, Wang Y  Inhaled nitric oxide: can it serve as a savior for COVID-19 and related respiratory and cardiovascular diseases?  Front Microbiol  2023;14:1277552. pii:1277552
  28. Sanchez-Pinto LN, Bhavani SV, Atreya MR, Sinha P  Leveraging Data Science and Novel Technologies to Develop and Implement Precision Medicine Strategies in Critical Care.  Crit Care Clin  2023 Oct;39(4):627-646. doi:10.1016/j.ccc.2023.03.002
  29. Machut KZ, Gilbart C, Murthy K, Michelson KN  A Qualitative Study of Nurses' Perspectives on Neonatologist Continuity of Care.  Adv Neonatal Care  2023 Oct 01;23(5):467-477. doi:10.1097/ANC.0000000000001096
  30. Sanchez-Pinto LN, Bennett TD, Stroup EK, Luo Y, Atreya M, Bubeck Wardenburg J, Chong G, Geva A, Faustino EVS, Farris RW  et al.  Derivation, Validation, and Clinical Relevance of a Pediatric Sepsis Phenotype With Persistent Hypoxemia, Encephalopathy, and Shock.  Pediatr Crit Care Med  2023 Oct 01;24(10):795-806. doi:10.1097/PCC.0000000000003292
  31. Zhou Z, Zhang Y, Tan C, Zhang J, Yi G, Wang B, Li Y, Lu H, Lu W, Zhang X  The long non-coding RNA BBOX1 antisense RNA 1 is upregulated in polycystic ovary syndrome (PCOS) and suppresses the role of microRNA-19b in the proliferation of ovarian granulose cells : Short title: BBOX1 antisense RNA 1 in cell proliferation.  BMC Womens Health  2023 Sep 21;23(1):508. pii:508
  32. Stephen RJ, Lucey K, Carroll MS, Hoge J, Maciorowski K, Jones RC, O'Connell M, Schwab C, Rojas J, Sanchez Pinto LN  Sepsis Prediction in Hospitalized Children: Clinical Decision Support Design and Deployment.  Hosp Pediatr  2023 Sep 01;13(9):751-759. doi:10.1542/hpeds.2023-007218
  33. Stephen RJ, Carroll MS, Hoge J, Maciorowski K, Jones RC, Lucey K, O'Connell M, Schwab C, Rojas J, Sanchez-Pinto LN  Sepsis Prediction in Hospitalized Children: Model Development and Validation.  Hosp Pediatr  2023 Sep 01;13(9):760-767. doi:10.1542/hpeds.2022-006964
  34. Zhang X, Brody JA, Graff M, Highland HM, Chami N, Xu H, Wang Z, Ferrier K, Chittoor G, Josyula NS  et al.  WHOLE GENOME SEQUENCING ANALYSIS OF BODY MASS INDEX IDENTIFIES NOVEL AFRICAN ANCESTRY-SPECIFIC RISK ALLELE.  medRxiv  2023 Aug 22;. pii:2023.08.21.23293271
  35. Atreya MR, Bennett TD, Geva A, Faustino EVS, Rogerson CM, Lutfi R, Cvijanovich NZ, Bigham MT, Nowak J, Schwarz AJ  et al.  External validation and biomarker assessment of a high-risk, data-driven pediatric sepsis phenotype characterized by persistent hypoxemia, encephalopathy, and shock.  Res Sq  2023 Aug 02;. pii:rs.3.rs-3216613
  36. Zhang X, Young C, Liao XH, Refetoff S, Torres M, Tomer Y, Stefan-Lifshitz M, Zhang H, Larkin D, Fang D  et al.  Perturbation of endoplasmic reticulum proteostasis triggers tissue injury in the thyroid gland.  JCI Insight  2023 Jun 22;8(12). pii:e169937
  37. Siddiqui MR, Reddy NM, Faridi HM, Shahid M, Shanley TP  Metformin alleviates lung-endothelial hyperpermeability by regulating cofilin-1/PP2AC pathway.  Front Pharmacol  2023;14:1211460. pii:1211460
  38. Zhao Y, Han X, Li C, Liu Y, Cheng J, Adhikari BK, Wang Y  COVID-19 and the cardiovascular system: a study of pathophysiology and interpopulation variability.  Front Microbiol  2023;14:1213111. pii:1213111
  39. Premkumar A, Fry JT, Bolden JR, Grobman WA, Michelson KN  The value and limitations of using predetermined criteria in decision making for maternal-fetal interventions.  Prenat Diagn  2023 Jun;43(6):792-797. doi:10.1002/pd.6363
  40. Pendergrast TR, Chapin CA, Kriegermeier AA, Pardo AC, Bass LM, Sanchez-Pinto LN  Heart rate variability is associated with encephalopathy and outcomes in pediatric acute liver failure.  Pediatr Res  2023 Apr;93(5):1348-1353. doi:10.1038/s41390-022-02225-2
  41. Rissman L, Derrington S, Michelson KN  Prognostic Conversations Between Parents and Physicians in the Pediatric Intensive Care Unit.  Am J Crit Care  2023 Mar 01;32(2):118-126. doi:10.4037/ajcc2023729
  42. Sanchez-Pinto LN, Sauthier M, Rajapreyar P, Brunow de Carvalho W, Jouvet P, Newth C,   Leveraging Clinical Informatics and Data Science to Improve Care and Facilitate Research in Pediatric Acute Respiratory Distress Syndrome: From the Second Pediatric Acute Lung Injury Consensus Conference.  Pediatr Crit Care Med  2023 Feb 01;24(12 Suppl 2):S1-S11. doi:10.1097/PCC.0000000000003155
  43. Divakar A, James K, Mayorga A, Michelson KN  Availability of bereavement support following traumatic pediatric death in a large metropolitan area.  Death Stud  2023;47(10):1127-1135. doi:10.1080/07481187.2023.2170492
  44. Olszewski AE, Mendelsohn L, Paquette ET  Unique Ethical and Practical Considerations in the Use of Behavior Contracts for Families of Minors and Minoritized Populations in Pediatric Settings.  Am J Bioeth  2023 Jan;23(1):82-85. doi:10.1080/15265161.2022.2146796
  45. Walker SB, Badke CM, Carroll MS, Honegger KS, Fawcett A, Weese-Mayer DE, Sanchez-Pinto LN  Novel approaches to capturing and using continuous cardiorespiratory physiological data in hospitalized children.  Pediatr Res  2023 Jan;93(2):396-404. doi:10.1038/s41390-022-02359-3

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